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Core Evidence
Vol. 2, No. 4
July, 2008
ISSN: 1555-1741
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Features and Benefits
Core Evidence is the first international peer-reviewed journal to rigorously evaluate the evidence for rational drug selection based on outcomes central to informed medical decision making, with the goal of improved quality of care

Core Evidence is unique because it:

Focuses on clinical outcomes evidence
Reviews the emerging evidence at key stages of drug development and evaluates how this may affect a drug’s place in therapy
Conducts a rigorous review of the evidence based on:
  Relevance: formulary guideline requirements provide
the structure
  Validity: evidence-based medicine techniques evaluate
the evidence
  Credibility: input from international experts weights the evidence according to clinical relevance
Core Evidence has a number of unique features
Feature Benefit
Evidence base table and methods
Clearly states the search terms, sources, inclusions and exclusions, and volume of evidence
At a glance identify the volume and level of evidence reviewed, and how it was selected
Clinical and economic
evidence review

The evidence is reviewed for each outcome, and its strengths and weaknesses evaluated using Core Evidence Evaluation Checklists
Identify the key outcomes

Assess the evidence quickly and credibly

Evidence summary
A proprietary method is used to factor the strength, weight, and consistency of evidence for each outcome, and its clinical implication is assessed
Synopsis of the evidence
of a drug’s effectiveness on each outcome according to its relevance

Clinical implications identified from the evidence